"Three Needles" is a drama that visits rural China, a plantation in South Africa, and Montreal's porn industry, to tell three separate yet universal stories, rooted to struggles with the HIV pandemic. In China, Ping is a pregnant young woman running a black market blood collection scam that creates a mini epidemic in a rural village. In Montreal, Denys is a porn actor hiding his positive HIV status in order to continue working and supporting his mother--who herself goes to extreme lengths to provide for the family's future. And, in Africa, Sister Clara is a young novice nun, driven to convert the rapidly dying Africans to Catholicism before it's too late; she makes a desperate bargain with a corrupt plantation owner to help prevent the spread of HIV in the region, bringing two nuns, who are of her same order, to accompany her on the journey.